Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PMVK antibody (Middle Region)

PMVK Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032231
$635.25
Plus shipping costs $45.00
100 μg
Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target See all PMVK Antibodies
    PMVK (Phosphomevalonate Kinase (PMVK))
    Binding Specificity
    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat
    Host
    • 33
    • 7
    Rabbit
    Clonality
    • 33
    • 6
    Polyclonal
    Conjugate
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PMVK antibody is un-conjugated
    Application
    • 23
    • 13
    • 13
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the middle region of human PMVK (EQSRQQRGWVFTPGVDD) was used as the immunogen for this PMVK antibody (100% homologous in human and mouse).
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the PMVK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the PMVK antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PMVK (Phosphomevalonate Kinase (PMVK))
    Alternative Name
    PMVK (PMVK Products)
    Synonyms
    MPK_Bm antibody, F5M6.9 antibody, F5M6_9 antibody, zgc:162701 antibody, HUMPMKI antibody, PMK antibody, PMKA antibody, PMKASE antibody, 1110011E12Rik antibody, 2900002L22Rik antibody, AV001327 antibody, phosphomevalonate kinase antibody, GHMP kinase family protein antibody, PMVK antibody, Mpk antibody, AT1G31910 antibody, CpipJ_CPIJ015413 antibody, Bm1_05275 antibody, pmvk antibody, LOAG_11811 antibody, Tsp_06629 antibody, LOC100282968 antibody, Pmvk antibody
    Background
    Phosphomevalonate kinase is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence(PTS-1), Ser-Arg-Leu, at the C terminus of the protein.
    UniProt
    Q15126
You are here:
Support