SERPINC1 antibody (N-Term)

Catalog No. ABIN3032537

The Rabbit Polyclonal anti-SERPINC1 antibody has been validated for WB. It is suitable to detect SERPINC1 in samples from Human, Mouse and Rat.

Quick Overview for SERPINC1 antibody (N-Term) (ABIN3032537)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SERPINC1 Antibody

Binding Specificity: N-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human AT3 (TFYQHLADSKNDNDN) was used as the immunogen for this Antithrombin III antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Antithrombin III antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Antithrombin III antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for SERPINC1

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: Antithrombin III

Background: Antithrombin III (AT3), is the most important inhibitor of thrombin and other coagulation proteinases. It is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

UniProt: P01008