CYLD antibody (AA 618-956)

Catalog No. ABIN3042782

Product Details anti-CYLD Antibody

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Binding Specificity: AA 618-956

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYLD antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ubiquitin carboxyl-terminal hydrolase CYLD(CYLD) detection. Tested with WB in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Ubiquitin carboxyl-terminal hydrolase CYLD(CYLD) detection. Tested with WB in Human,Rat.
Gene Name: cylindromatosis (turban tumor syndrome)
Protein Name: Ubiquitin carboxyl-terminal hydrolase CYLD

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Alternative Name: CYLD (CYLD Products)

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: BRSS antibody|CDMT antibody|Cyld antibody|CYLD gene antibody|CYLD_HUMAN antibody|CYLD1 antibody|CYLDI antibody|cylindromatosis (turban tumor syndrome) antibody|cylindromatosis 1 antibody|Deubiquitinating enzyme CYLD antibody|EAC antibody|HSPC057 antibody|KIAA0849 antibody|MFT antibody|MFT1 antibody|Probable ubiquitin carboxyl terminal hydrolase CYLD antibody|SBS antibody|TEM antibody|turban tumor syndrome antibody|Ubiquitin carboxyl-terminal hydrolase CYLD antibody|ubiquitin specific peptidase like 2 antibody|ubiquitin thioesterase CYLD antibody|Ubiquitin thiolesterase CYLD antibody|Ubiquitin-specific processing protease CYLD antibody|Ubiquitin-specific-processing protease CYLD antibody| USPL2 antibody

Gene ID: 1540

Pathways: Apoptosis, Activation of Innate immune Response