Interleukin 17a antibody (AA 26-158)

Catalog No. ABIN3042799

This Rabbit Polyclonal antibody specifically detects Interleukin 17a in ELISA and WB. It exhibits reactivity toward Mouse and has been mentioned in 2+ publications.

Quick Overview for Interleukin 17a antibody (AA 26-158) (ABIN3042799)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Interleukin 17a Antibody

Binding Specificity: AA 26-158

Purpose: Anti-IL17/IL17A Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-IL17/IL17A Antibody (ABIN3042799). Tested in ELISA, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse IL-17 recombinant protein (Position: A26-A158).

Isotype: IgG

Application Details

Application Notes: ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Mouse

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free or No BSA in your order note.

Preservative: Sodium azide, Without preservative

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Interleukin 17a antibody (ABIN3042799)

Li, Pan, Qiu: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).

Ma, Wang, Zhao, Pang, Zhang, Jiang, Liu, Mamuti, Wen, Ding: "Th17 cells are associated with the Th1/Th2?cell balance during Echinococcus multilocularis infection." in: Molecular medicine reports, Vol. 10, Issue 1, pp. 236-40, (2014) (PubMed).

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL17A

Background:

Synonyms: Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,Il17a,Ctla8, Il17,

Tissue Specificity: Restricted to a subset of activated T-cells. .

Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Sequence Similarities: Belongs to the immunoglobulin superfamily. CEA family.

Molecular Weight: 30 kDa

UniProt: Q62386