LI Cadherin antibody (C-Term)

Catalog No. ABIN3042838

This Rabbit Polyclonal antibody specifically detects LI Cadherin in WB. It exhibits reactivity toward Human.

Quick Overview for LI Cadherin antibody (C-Term) (ABIN3042838)

Target: LI Cadherin

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LI Cadherin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LI Cadherin Antibody

Binding Specificity: AA 686-699, C-Term

Purpose: Anti-LI-Cadherin-17 CDH17-Antibody

Sequence: LIFEATDDDQ HLFR

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-LI-Cadherin-17 CDH17-Antibody (ABIN3042838). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LI Cadherin.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LI Cadherin

Target: LI Cadherin

Alternative Name: CDH17

Background:

Synonyms: Cadherin-17,Intestinal peptide-associated transporter HPT-1,Liver-intestine cadherin,LI-cadherin,CDH17,

Tissue Specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. .

Background: Cadherin-17, also known as HPT1 or CDH16 is a protein that in humans is encoded by the CDH17 gene. By somatic cell hybrid analysis and fluorescence in situ hybridization, CDH17 gene is mapped to 8q22.1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Sequence Similarities: Contains 7 cadherin domains.

Molecular Weight: 92 kDa

UniProt: Q12864