LI Cadherin antibody (C-Term)

Catalog No. ABIN3042838

This Rabbit Polyclonal antibody specifically detects LI Cadherin in WB. It exhibits reactivity toward Human.

Quick Overview for LI Cadherin antibody (C-Term) (ABIN3042838)

Target: LI Cadherin

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LI Cadherin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LI Cadherin Antibody

Binding Specificity: AA 686-699, C-Term

Purpose: Anti-LI-Cadherin-17 CDH17-Antibody Picoband®

Sequence: LIFEATDDDQ HLFR

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-LI-Cadherin-17 CDH17-Antibody (ABIN3042838). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LI Cadherin.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Dantzig, A. H., Hoskins, J., Tabas, L. B., Bright, S., Shepard, R. L., Jenkins, I. L., Duckworth, D. C., Sportsman, J. R., Mackensen, D., Rosteck, P. R., Jr., Skatrud, P. L. Association of intestinal peptide transport with a protein related to the cadherin superfamily. cience 264: 430-433, 1994. 2. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LI Cadherin

Target: LI Cadherin

Alternative Name: CDH17

Background:

Synonyms: Cadherin-17,Intestinal peptide-associated transporter HPT-1,Liver-intestine cadherin,LI-cadherin,CDH17,

Tissue Specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. .

Background: Cadherin-17, also known as HPT1 or CDH16 is a protein that in humans is encoded by the CDH17 gene. By somatic cell hybrid analysis and fluorescence in situ hybridization, CDH17 gene is mapped to 8q22.1. This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Sequence Similarities: Contains 7 cadherin domains.

Molecular Weight: 92 kDa

UniProt: Q12864