CX3CL1 antibody (C-Term)

Catalog No. ABIN3042907

This Rabbit Polyclonal antibody specifically detects CX3CL1 in WB and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CX3CL1 antibody (C-Term) (ABIN3042907)

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CX3CL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CX3CL1 Antibody

Binding Specificity: AA 646-659, C-Term

Purpose: Anti-PMP70/ABCD3 Antibody Picoband®

Sequence: EFKQITEDTV EFGS

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-PMP70/ABCD3 Antibody (ABIN3042907). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PMP70, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Rat, Human, Mouse
1. Gartner J, Moser H, Valle D (June 1993). "Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome".Nat Genet 1 (1): 16-23. 2. Gartner J, Kearns W, Rosenberg C, Pearson P, Copeland NG, Gilbert DJ, Jenkins NA, Valle D (April 1993). "Localization of the 70- kDa peroxisomal membrane protein to human 1p21-p22 and mouse 3". Genomics 15 (2): 412-4. 3. "Entrez Gene: ABCD3 ATP-binding cassette, sub-family D (ALD), member 3".

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CX3CL1

Target: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Alternative Name: ABCD3

Background:

Synonyms: ATP-binding cassette sub-family D member 3,70 kDa peroxisomal membrane protein,PMP70,ABCD3,PMP70, PXMP1,

Background: ATP-binding cassette sub-family D member 3 is a protein that in humans is encoded by the ABCD3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene was assigned to human chromosome 1p21-p22 by in situ hybridization. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders.

Sequence Similarities: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.

Molecular Weight: 142 kDa

UniProt: P28288

Pathways: Synaptic Membrane