LAMP1 antibody (C-Term)

Catalog No. ABIN3043036

Product Details anti-LAMP1 Antibody

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Binding Specificity: AA 403-417, C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Lysosome-associated membrane glycoprotein 1(LAMP1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: YLVGRKRSHA GYQTI

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Lysosome-associated membrane glycoprotein 1(LAMP1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: lysosomal-associated membrane protein 1
Protein Name: Lysosome-associated membrane glycoprotein 1(LAMP-1)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LAMP1(403-417aa YLVGRKRSHAGYQTI), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: LAMP1 (LAMP1 Products)

Background: LAMP1(lysosomal-associated membrane protein 1) also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al.(1990) assigned the LAMP1 gene to chromosome 13q34. A related gene, which may be a pseudogene, mapped to chromosome 12p13.3. Hybridization of LAMP1 cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1 cDNA were used.

Synonyms: CD107 antigen like family member A antibody|CD107 antigen-like family member A antibody|CD107a antibody|CD107a antigen antibody|LAMP 1 antibody|LAMP-1 antibody|LAMP1 antibody|LAMP1_HUMAN antibody|LAMPA antibody|LGP120 antibody|lgpA antibody|Lysosomal membrane glycoprotein 120KD antibody|Lysosomal Associated Membrane Protein 1 antibody|Lysosome associated membrane glycoprotein 1 antibody|Lysosome-associated membrane glycoprotein 1 antibody|Lysosome-associated membrane protein 1 antibody|OTTHUMP00000040663 antibody

UniProt: P11279

Pathways: Autophagy