LAMP1 antibody (N-Term)

Catalog No. ABIN388566

Cited in 4+ publications. The Rabbit Polyclonal anti-LAMP1 antibody (Clone RB12577) (ABIN388566) specifically detects LAMP1 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for LAMP1 antibody (N-Term) (ABIN388566)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB12577

Product Details anti-LAMP1 Antibody

Binding Specificity: AA 125-154, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LAMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the N-terminal region of human LAMP1.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-LAMP1 antibody (ABIN388566)

Funk, Mrak, Kuret: "Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles." in: Neuropathology and applied neurobiology, Vol. 37, Issue 3, pp. 295-306, (2011) (PubMed).

Kim, Woo, Yoon, Lee, An, Choi, Hwang, Yoon, Lee: "Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 12924-32, (2011) (PubMed).

Hnasko, Lin, McGarvey, Stanker: "A rapid method to improve protein detection by indirect ELISA." in: Biochemical and biophysical research communications, Vol. 410, Issue 4, pp. 726-31, (2011) (PubMed).

Byun, Yoon, An, Park, Kang, Kim, Lee: "The Rac1/MKK7/JNK pathway signals upregulation of Atg5 and subsequent autophagic cell death in response to oncogenic Ras." in: Carcinogenesis, Vol. 30, Issue 11, pp. 1880-8, (2009) (PubMed).

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: LAMP1

Background: LAMP1 is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.

Molecular Weight: 44882

Gene ID: 3916

NCBI Accession: NP_005552

UniProt: P11279

Pathways: Autophagy