SSTR1 antibody (C-Term)

Catalog No. ABIN3043098

Product Details anti-SSTR1 Antibody

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Binding Specificity: AA 361-381, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSTR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Anti-Somatostatin Receptor 1/SSTR1 Antibody Picoband®

Sequence: RAYSVEDFQP ENLESGGVFR N

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Somatostatin Receptor 1/SSTR1 Antibody (ABIN3043098). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin Receptor 1, identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Rat, Human, Mouse
1. Kubota, A., Yamada, Y., Kagimoto, S., Shimatsu, A., Imamura, M., Tsuda, K., Imura, H., Seino, S., Seino, Y.Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors.J. Clin. Invest. 93: 1321-1325, 1994. 2. Yamada, Y., Post, S. R., Wang, K., Tager, H. S., Bell, G. I., Seino, S.Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.Proc. Nat. Acad. Sci. 89: 251-255, 1992.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-SSTR1 antibody (ABIN3043098)

Guo, Shi, Zhou, Chen: "Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 7, pp. 4071-5, (2013) (PubMed).

Target Details for SSTR1

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Alternative Name: SSTR1 (SSTR1 Products)

Background:

Synonyms: Somatostatin receptor type 1,SS-1-R,SS1-R,SS1R,SRIF-2,SSTR1,

Tissue Specificity: Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.

Background: SSTR1 (Somatostatin receptor type 1) is a protein that in humans is encoded by the SSTR1 gene. The SSTR1 gene is mapped to chromosome 14. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.

Sequence Similarities: Belongs to the transcription factor STAT family.

Molecular Weight: 60 kDa

UniProt: P30872