STRA8 antibody (C-Term)

Catalog No. ABIN3043103

The Rabbit Polyclonal anti-STRA8 antibody has been validated for WB. It is suitable to detect STRA8 in samples from Human.

Quick Overview for STRA8 antibody (C-Term) (ABIN3043103)

Target: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRA8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STRA8 Antibody

Binding Specificity: AA 313-330, C-Term

Purpose: Anti-Stra8 Antibody Picoband®

Sequence: DEEMIMLQCT ETFDDEDL

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Stra8 Antibody (ABIN3043103). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Stra8.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. Anderson, E. L., Baltus, A. E., Roepers-Gajadien, H. L., Hassold, T. J., de Rooij, D. G., van Pelt, A. M. M., Page, D. C.Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.Proc. Nat. Acad. Sci. 105: 14976-14980, 2008. 2. Miyamoto, T., Sengoku, K., Takuma, N., Hasuike, S., Hayashi, H., Yamauchi, T., Yamashita, T., Ishikawa, M.Isolation and expression analysis of the testis-specific gene, STRA8, stimulated by retinoic acid gene 8.J. Assisted Reprod. Genet. 19: 531-535, 2002.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STRA8

Target: STRA8 (Stimulated By Retinoic Acid 8 (STRA8))

Alternative Name: STRA8

Background:

Synonyms: Stimulated by retinoic acid gene 8 protein homolog,STRA8 ,

Tissue Specificity: Expressed specifically in testis. .

Background: Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

Molecular Weight: 55 kDa

UniProt: Q7Z7C7