CD90 antibody (N-Term)

Catalog No. ABIN3043174

Product Details anti-CD90 Antibody

Target: CD90 (THY1)

Binding Specificity: AA 20-39, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD90 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Anti-CD90/Thy1 Antibody Picoband®

Sequence: QKVTSLTACL VDQSLRLDCR

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-CD90/Thy1 Antibody (ABIN3043174). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human CD90, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Rat, Human, Mouse
1. Abeysinghe, H. R., Cao, Q., Xu, J., Pollock, S., Veyberman, Y., Guckert, N. L., Keng, P., Wang, N.THY1 expression is associated with tumor suppression of human ovarian cancer.Cancer Genet. Cytogenet. 143: 125-132, 2003. 2. McKenzie, J. L., Fabre, J. W.Human Thy-1: unusual localization and possible functional significance in lymphoid tissues.J. Immun. 126: 843-850, 1981. 3. Morris, R.Thy-1 in developing nervous tissue.Dev. Neurosci. 7: 133-160, 1985.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-CD90 antibody (ABIN3043174)

Tian, Tao, Zhao, Tai, Liu, Liu: "Isolation and morphological characterization of ovine amniotic fluid mesenchymal stem cells." in: Experimental animals, Vol. 65, Issue 2, pp. 125-34, (2017) (PubMed).

Zhang, Shang, Hao, Zheng, Li, Liang, Cui, Liu: "Effects of human umbilical cord mesenchymal stem cell transplantation combined with minimally invasive hematoma aspiration on intracerebral hemorrhage in rats." in: American journal of translational research, Vol. 7, Issue 11, pp. 2176-86, (2016) (PubMed).

Li, Xu, Xu, Xu, Zhao, Zhang: "Fms-related tyrosine kinase 3 ligand promotes proliferation of placenta amnion and chorion mesenchymal stem cells in vitro." in: Molecular medicine reports, Vol. 10, Issue 1, pp. 322-8, (2014) (PubMed).

Huang, Jia, Bai, Gong, Fan: "Effect of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells." in: Archives of medical research, Vol. 41, Issue 7, pp. 497-505, (2010) (PubMed).

Target Details for CD90

Target: CD90 (THY1)

Alternative Name: THY1 (THY1 Products)

Background:

Synonyms: Thy-1 membrane glycoprotein;CDw90;Thy-1 antigen;CD90;THY1;

Background: CD90 (Cluster of Differentiation 90) or Thy-1 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen. The CD90 gene is mapped to 11q23.3. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of Thy-1 lead to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor.

Sequence Similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Molecular Weight: 22 kDa

UniProt: P04216

Pathways: Cell-Cell Junction Organization