ANGPTL1 antibody (C-Term)

Catalog No. ABIN3043187

The Rabbit Polyclonal anti-ANGPTL1 antibody has been validated for WB. It is suitable to detect ANGPTL1 in samples from Human, Mouse and Rat.

Quick Overview for ANGPTL1 antibody (C-Term) (ABIN3043187)

Target: ANGPTL1 (Angiopoietin-Like 1 (ANGPTL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANGPTL1 Antibody

Binding Specificity: AA 477-491, C-Term

Purpose: Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody Picoband®

Sequence: SYSLRAVQMM IKPID

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Angiopoietin-related protein 1 ANGPTL1 Antibody (ABIN3043187). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ANGPTL1, identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Kim, I., Kwak, H. J., Ahn, J. E., So, J.-N., Liu, M., Koh, K. N., Koh, G. Y.Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin-3.FEBS Lett. 443: 353-356, 1999.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANGPTL1

Target: ANGPTL1 (Angiopoietin-Like 1 (ANGPTL1))

Alternative Name: ANGPTL1

Background:

Synonyms: Angiopoietin-related protein 1,Angiopoietin-3,ANG-3,Angiopoietin-like protein 1,ANGPTL1,ANG3, ANGPT3, ARP1,PSEC0154, UNQ162/PRO188,

Tissue Specificity: Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach. .

Background: ANGPTL1, Angiopoietin-related protein 1, is a protein that in humans is encoded by the ANGPTL1 gene. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. ANGPTL1 is widely expressed in human adult tissues as a major 3.0-kb transcript and a less abundant 4.0-kb transcript.

Sequence Similarities: Belongs to the glycosyl hydrolase 13 family.

Molecular Weight: 55-58 kDa

UniProt: O95841