SRSF3 antibody (N-Term)

Catalog No. ABIN3043298

The Rabbit Polyclonal anti-SRSF3 antibody has been validated for WB, IF, ICC and FACS. It is suitable to detect SRSF3 in samples from Human.

Quick Overview for SRSF3 antibody (N-Term) (ABIN3043298)

Target: SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRSF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-SRSF3 Antibody

Binding Specificity: AA 1-29, N-Term

Purpose: Anti-SFRS3/SRSF3 Antibody Picoband®

Sequence: MHRDSCPLDC KVYVGNLGNN GNKTELERA

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SFRS3/SRSF3 Antibody Picoband® (ABIN3043298). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SFRS3, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
1. "Entrez Gene: SFRS3 splicing factor, arginine/serine-rich 3". 2. Zahler AM, Lane WS, Stolk JA, Roth MB (Jun 1992). "SR proteins: a conserved family of pre-mRNA splicing factors". Genes Dev 6 (5): 837-47.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for SRSF3

Target: SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

Alternative Name: SRSF3

Background:

Synonyms: Serine/arginine-rich splicing factor 3,Pre-mRNA-splicing factor SRP20,Splicing factor, arginine/serine-rich 3,SRSF3,SFRS3, SRP20,

Tissue Specificity: Ubiquitously expressed.

Background: Splicing factor, arginine/serine-rich 3, also known as SRSF3, is a protein that in humans is encoded by the SFRS3 gene. The protein encoded by this gene is a member of the serine/ arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.

Sequence Similarities: Belongs to the splicing factor SR family.

Molecular Weight: 19 kDa

Gene ID: 6428

UniProt: P84103