S100A11 antibody (AA 2-105)

Catalog No. ABIN3043319

The Rabbit Polyclonal anti-S100A11 antibody has been validated for WB. It is suitable to detect S100A11 in samples from Human.

Quick Overview for S100A11 antibody (AA 2-105) (ABIN3043319)

Target: S100A11 (S100 Calcium Binding Protein A11 (S100A11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-S100A11 Antibody

Binding Specificity: AA 2-105

Purpose: Anti-S100A11 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-A11 Antibody Picoband® (ABIN3043319). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human S100A11 recombinant protein (Position: A2-T105). Human S100A11 shares 86.7% amino acid (aa) sequence identity with both mouse and rat S100A11.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: S100A11 S100 calcium binding protein A11". 2. Sakaguchi, M., Sonegawa, H., Murata, H., Kitazoe, M., Futami, J., Kataoka, K., Yamada, H., Huh, N. S100A11, an (sic) dual mediator for growth regulation of human keratinocytes. Molec. Biol. Cell 19: 78-85, 2008. 3. Wicki R, Marenholz I, Mischke D, Schäfer BW, Heizmann CW (March 1997). "Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21".Cell Calcium 20 (6): 459-64.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for S100A11

Target: S100A11 (S100 Calcium Binding Protein A11 (S100A11))

Alternative Name: S100A11

Background:

Synonyms: Protein S100-A11,Calgizzarin,Metastatic lymph node gene 70 protein,MLN 70,Protein S100-C,S100 calcium-binding protein A11,Protein S100-A11, N-terminally processed,S100A11,MLN70, S100C,

Tissue Specificity: Overexpressed in bladder cancer cells (PubMed:17409436). .

Background: S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. And S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.

Molecular Weight: 15 kDa

Gene ID: 6282

UniProt: P31949

Pathways: S100 Proteins