SLC16A4 antibody (N-Term)

Catalog No. ABIN3044003

The Rabbit Polyclonal anti-SLC16A4 antibody has been validated for WB and IHC. It is suitable to detect SLC16A4 in samples from Human, Mouse and Rat.

Quick Overview for SLC16A4 antibody (N-Term) (ABIN3044003)

Target: SLC16A4 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 4 (SLC16A4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLC16A4 Antibody

Binding Specificity: AA 134-148, N-Term

Purpose: Anti-Monocarboxylate transporter 5 SLC16A4 Antibody Picoband®

Sequence: VVTTKYFKKR LALST

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-Monocarboxylate transporter 5 SLC16A4 Antibody (ABIN3044003). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC16A4, different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Biankin, A. V., Waddell, N., Kassahn, K. S., Gingras, M.-C., Muthuswamy, L. B., Johns, A. L., Miller, D. K., Wilson, P. J., Patch, A.-M., Wu, J., Chang, D. K., Cowley, M. J., and 116 others. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature 491: 399-405, 2012. 2. Yoon, H., Donoso, L. A., Philp, N. J. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2. Genomics 60: 366-370, 1999.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SLC16A4

Target: SLC16A4 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 4 (SLC16A4))

Alternative Name: SLC16A4

Background:

Synonyms: Monocarboxylate transporter 5,MCT 5,Monocarboxylate transporter 4,MCT 4,Solute carrier family 16 member 4,SLC16A4,MCT4, MCT5,

Tissue Specificity: Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.

Background: Monocarboxylate transporter 5, also called Solute carrier family 16 member 4 or MCT4, is a protein that in humans is encodes by the SLC16A4 gene. This gene is mapped to 1p13.3. It acts as the proton-linked monocarboxylate transporter. This gene catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Sequence Similarities: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.

Molecular Weight: 274 kDa

UniProt: O15374