Clusterin antibody (AA 1-333)

Catalog No. ABIN306419

Product Details anti-Clusterin Antibody

Target: Clusterin (CLU)

Binding Specificity: AA 1-333

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Clusterin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human Clusterin (1-333aa) purified from E. coli

Clone: 1A11

Isotype: IgG1 kappa

Application Details

Application Notes: Recommended dilution 1:1000(W.B), Recommended dilution 1:100(IHC)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for Clusterin

Target: Clusterin (CLU)

Alternative Name: Clusterin/CLU (CLU Products)

Background: Clusterin has been implicated in numerous processes including active cell death, immune regulation, cell adhesion and morphological transformation. Clusterin (previousiy named SP-40) is a glycoprotein, 80 kDa comprising two distinct 40 kDa polypeptide chains. It shows marked similarity, both physicochemically and in immunohistological distribution, to the single chain, 80 kDa, Sprotein, an additional component of the SC5b-9 complex. Clusterin is a secreted glycoprotein of which the exact function remains a matter for speculation.

NCBI Accession: NP_001822

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling