SUPT16H antibody (AA 321-640)

Catalog No. ABIN306913

This Rabbit Polyclonal antibody specifically detects SUPT16H in WB and IP. It exhibits reactivity toward Human.

Quick Overview for SUPT16H antibody (AA 321-640) (ABIN306913)

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUPT16H antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SUPT16H Antibody

Binding Specificity: AA 321-640

Cross-Reactivity: Human, Mouse

Characteristics: SSRP1,SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.

Purification: Ammonium Sulfate Precipitation

Immunogen: Recombinant protein consisting of amino acids 321-640 of the human SPT16 protein conjugated to KLH.

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 μg/mL) and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for SUPT16H

Target: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Alternative Name: SPT16 (Intermediate Domain)

UniProt: Q9Y5B9

Pathways: Chromatin Binding