FKBP4 antibody
Quick Overview for FKBP4 antibody (ABIN307239)
Target
See all FKBP4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Recognizes rabbit FKBP59. Has been shown to block the ability of FK506 to promote neurite outgrowth from SH--SY5Y cells in a concentration-dependent manner between 50-100nM. Species cross-reactivity: Human, monkey, bovine, mink, rabbit, hamster and guinea pig (weakly).
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Purification
- Protein G purified
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Immunogen
- Partially purified 9S rabbit uterine progesterone receptor.
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Isotype
- IgG1
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Application Notes
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Approved: ELISA, ICC, IHC (1:3000), IP (10 μg/mL), RIA, WB (2 μg/mL)
Usage: Suitable for use in Western Blot, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry, RIA, ELISA and as a Blocking Antibody. Western Blot (Colorimetric): 2 μg/mL. Detects ~59kD band. Additional unidentified 50kD band observed in some cell lysates. Immunoprecipitation: 10 μg/mL. Immunohistochemistry: 1:3000. Positive control: HeLa Heat Shocked Cell Lysate. -
Comment
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Target Species of Antibody: Rabbit
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.2, 50 % glycerol, 0.1 mM PMSF.
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Preservative
- PMSF
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))
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Alternative Name
- FKBP4 / FKBP52
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Background
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Name/Gene ID: FKBP4
Synonyms: FKBP4, 59 kDa immunophilin, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, 52 kDa FKBP, FKBP-52, FKBP51, HBI, Immunophilin FKBP52, FK506 binding protein 4, 59 kDa, FK506-binding protein 4, HSP56, p52, p59, Rotamase, p59 protein, PPIase, PPIase FKBP4, FKBP-4, FKBP52, FKBP59, HSP binding immunophilin, HSP-binding immunophilin -
Gene ID
- 2288
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UniProt
- Q02790
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
Target
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