PACRG antibody (AA 204-215)
Quick Overview for PACRG antibody (AA 204-215) (ABIN308675)
Target
See all PACRG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 204-215
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Cross-Reactivity
- Human, Rat (Rattus)
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Purification
- affinity purified
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Immunogen
- Synthetic peptide containing AA 204-215 of Human PACRG protein.
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- -20 °C
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- PACRG (PARK2 Co-Regulated (PACRG))
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Background
- PACRG (also known as Parkin coregulated gene protein and PARK2 coregulated) is a gene located very close to parkin, in reverse orientation on the chromosome. It is thought to be co-transcribed with parkin by a bi-directional promoter between the two genes. PACRG is expressed in all immune tissues, spleen, lymph nodes, thymus, tonsils, leukocyte and bone marrow and is also expressed in heart, brain, skeletal muscle, kidney, lung and pancreas. PACRG is expressed in primary Schwann cells and very weakly by monocyte-derived macrophages, which are the primary host cells of Mycobacterium leprae, the causative agent of leprosy. Splice variants have been described for this protein.
Target
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