Osteocalcin antibody

Catalog No. ABIN316665

This anti-Osteocalcin antibody is a Mouse Monoclonal antibody detecting Osteocalcin in EIA. Suitable for Human.

Quick Overview for Osteocalcin antibody (ABIN316665)

Target: Osteocalcin (BGLAP)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 6F9G4E10

Product Details anti-Osteocalcin Antibody

Specificity: This antibody recognizes intact Human Osteocalcin in a "2 site" assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-42 or intact Bovine Osteocalcin.

No Cross-Reactivity: Cow (Bovine), Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: Bone Gla protein, BGLAP, Gamma-carboxyglutamic acid-containing protein

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Recombinant Human Osteocalcin GST fusion protein

Isotype: IgG1

Application Details

Application Notes: ELISA. This antibody may be used in combination with ABIN316667 or ABIN180921 inSandwich ELISA assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: Osteocalcin

Background: Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.Synonyms: BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein

Gene ID: 632

UniProt: P02818