PSPH antibody (N-Term)

Catalog No. ABIN317527

This anti-PSPH antibody is a Mouse Monoclonal antibody detecting PSPH in WB, IHC (p) and EIA. Suitable for Human and Mouse.

Quick Overview for PSPH antibody (N-Term) (ABIN317527)

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSPH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3G12

Product Details anti-PSPH Antibody

Binding Specificity: AA 1-225, N-Term

Specificity: The antibody recognizes Phosphoserine Phosphatase.

Characteristics: Synonyms: PSPH, PSPase, PSP, EC=3.1.3.3, O-phosphoserine phosphohydrolase, L-3-phosphoserinephosphatase

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human PSP (1-225 aa) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1/1,000-1/2,000)Recommended Starting Dilution: 1/1,000. Immunohistochemistry on Paraffin Sections (10 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PSPH

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Alternative Name: Phosphoserine Phosphatase

Background: Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg(2+)-dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.Synonyms: EC=3.1.3.3, L-3-phosphoserine phosphatase, O-phosphoserine phosphohydrolase, PSP, PSPH, PSPase

Gene ID: 5723

UniProt: P78330

Pathways: Warburg Effect