MC5 Receptor antibody

Catalog No. ABIN317755

This Rabbit Polyclonal antibody specifically detects MC5 Receptor in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MC5 Receptor antibody (ABIN317755)

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC5 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MC5 Receptor Antibody

Specificity: MC5-R antibody detects endogenous levels of MC5-R protein. (region surrounding Glu308)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MC5 Receptor

Target: MC5 Receptor (MC5R) (Melanocortin 5 Receptor (MC5R))

Alternative Name: MC5-R

Background: The melanocortin family comprises the α-, β- and γ-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane, G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC-2, MC5R, Melanocortin receptor 5

Molecular Weight: approx. 40 kDa

Gene ID: 4161

NCBI Accession: NP_005904

UniProt: P33032

Pathways: cAMP Metabolic Process