Glucagon antibody (AA 8-18)

Catalog No. ABIN318562

This Goat Polyclonal antibody specifically detects Glucagon in EIA. It exhibits reactivity toward Human.

Quick Overview for Glucagon antibody (AA 8-18) (ABIN318562)

Target: Glucagon (GCG)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-Glucagon Antibody

Binding Specificity: AA 8-18

Specificity: This antibody detects glucagon.

Purification: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Synthetic peptide corresponding to amino acids 8-18 of human glucagon

Isotype: IgG

Application Details

Application Notes: ELISA: 1/200 - 1/20000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: Glucagon

Background: Glucagon is a pancreatic hormone whose actions are antagonistic to insulin, functioning to increase blood glucose through stimulation of glycogenolysis and gluconeogenesis in the liver. Glucagon is a ligand for the glucagon receptor, a G-protein linked receptor whose signalling pathway controls cell proliferation. Glucagon is secreted from A-cells within the Islets of Langerhans in the pancreas.Synonyms: GCG

Gene ID: 2641

NCBI Accession: NP_002045

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling