Osteocalcin antibody (AA 37-49)

Catalog No. ABIN318613

This Rabbit Polyclonal antibody specifically detects Osteocalcin in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Osteocalcin antibody (AA 37-49) (ABIN318613)

Target: Osteocalcin (BGLAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Osteocalcin Antibody

Binding Specificity: AA 37-49

Sequence: GFQEAYRRFY GPV

Specificity: This antibody is specific for human osteocalcin.

Purification: Purified IgG prepared by affinity chromatography on Protein G.

Immunogen: Synthetic peptide corresponding to amino acids 37 - 49 of human osteocalcin conjugated to Keyhole limpet Haemocyanin.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1/10 - 1/500. ELISA: 1/30 - 1/300.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: Phosphate buffered saline, pH 7.4 containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: Osteocalcin

Background: Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa) made by osteoblasts, that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Pagets disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.Synonyms: BGLAP, Bone Gla protein, Gamma-carboxyglutamic acid-containing protein

Gene ID: 632

NCBI Accession: NP_954642

UniProt: P02818