KLF4 antibody (N-Term)

Catalog No. ABIN336104

The Mouse Monoclonal anti-KLF4 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect KLF4 in samples from Human.

Quick Overview for KLF4 antibody (N-Term) (ABIN336104)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: AT4E6

Product Details anti-KLF4 Antibody

Binding Specificity: AA 1-170, N-Term

Specificity: The antibody recognizes human KLF4. Other species not tested.

Characteristics: Synonyms: EZF, GKL, Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enrichedkrueppel-like factor

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human KLF4 (aa 1-170) purified from E. coli

Isotype: IgG1

Application Details

Application Notes: ELISA. Western blot (1: 1,000 - 2,000). Immunohistochemistry on paraffin-embedded tissues (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: KLF4

Background: KLF4, which is also known as the gut-enriched Kruppel-like factor (GKLF), is a zinc finger-containing transcription factor that belongs to the Kruppel-like family of transcription factors. KLF4 plays important roles during the proliferation and differentiation of epithelial cells. Especially, it is found predominantly in gut and has been shown to be expressed during growth arrest. KLF4 is also involved in cell cycle control since expression of KLF4 inhibits DNA synthesis by blocking the G1/S phase of the cell cycle.Synonyms: EZF, Epithelial zinc finger protein EZF, GKL, Gut-enriched krueppel-like factor, Krueppel-like factor 4

Gene ID: 9314

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance