Bax Inhibitor 1 antibody

Catalog No. ABIN336116

The Rabbit Polyclonal anti-Bax Inhibitor 1 antibody has been validated for WB. It is suitable to detect Bax Inhibitor 1 in samples from Human, Mouse and Rat.

Quick Overview for Bax Inhibitor 1 antibody (ABIN336116)

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bax Inhibitor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Bax Inhibitor 1 Antibody

Specificity: The antibody detects BI-1

Purification: Affinity chromatography

Immunogen: Synthetic peptide corresponding to residues around amino acids 210 of human Bl-1.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.

Target Details for Bax Inhibitor 1

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Alternative Name: Bax Inhibitor 1

Background: Bl-1 (Bax inhibitor-1), also designated TEGT for testis enhanced gene transcript, was identified as an additional inhibitor of apoptosis. Bl-1 interacts with Bcl-2 and Bcl-xL, but not with Bax or Bak, to inhibit Bax induced apoptosis.Synonyms: BI-1, BI1, TEGT, TMBIM6, Testis-enhanced gene transcript protein, Transmembrane BAX inhibitor motif-containing protein 6

Gene ID: 7009

NCBI Accession: NP_001092046

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling