hCG antibody

Catalog No. ABIN336855

This anti-hCG antibody is a Mouse Monoclonal antibody detecting hCG in IHC and IHC (p). Suitable for Human.

Quick Overview for hCG antibody (ABIN336855)

Target: hCG (Chorionic Gonadotropin (hCG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This hCG antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HCG 205

Product Details anti-hCG Antibody

Specificity: Molecular Weight: 22 kDa.

Immunogen: Purified beta hCG

Isotype: IgG1 kappa

Application Details

Application Notes: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin-biotin system or polymer system, incubate 30 minutes at room temperature. Prediluted antibody is ready to be used for IHC. Antigen retriever like citrate enhances the staining of FFPE tissue sections (Boil tissue in 10 mM citrate, pH 6.0 for 10-15 minutes followed by cooling for 10-15 minutes at RT. The optimum dilution should be determined by the individual lab. Positive Control: Human placenta, choriocarcinoma. Cellular Localization: Cytoplasmic.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for hCG

Target: hCG (Chorionic Gonadotropin (hCG))

Alternative Name: Chorionic Gonadotropin

Target Type: Hormone

Background: Human chorionic gonadotropin (hCG) is a oligosaccharide glycopeptide hormone (244 aa) produced in pregnancy that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. hCG may have additional functions, for instance, it is thought that hCG affects the immune tolerance of the pregnancy. Early pregnancy testing, in general, is based on the detection or measurement of hCG. HCG is compose of two non-identical, non-covalently linked polypeptide chains as alpha and beta-subunits. The alpha subunit of hCG is nearly identical to that of thyroid stimulating (TSH), FSH, and LH.A germ cell tumor which is + for Cytokeratin, PLAP, and hCG but negative for EMA and alpha feto protein is probably choriocarcinoma