Histone 3 antibody (ciArg2, ciArg8, ciArg17)
Quick Overview for Histone 3 antibody (ciArg2, ciArg8, ciArg17) (ABIN347087)
Target
See all Histone 3 (H3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- ciArg2, ciArg8, ciArg17
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Specificity
- Reacts with human Histone H3 Citrulline at the 3 positions: 2, 8 and 17
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Cross-Reactivity (Details)
- Reacts with mono or di H3-Cit. Not tested in other species. May cross reacts with other species due to sequence homology.
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Purification
- Antiserum
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Immunogen
- Synthetic peptide derived from Nter domain of human Histone H3 containing Citrulline at position 2-8-17
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Isotype
- IgG
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/2 000 to 1/20 000 - WB : 1/5 000 to 1/50 000 -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Must be reconstituted in distilled water.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Expiry Date
- 24 months
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- Histone 3 (H3) (Histone H3 (H3))
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Alternative Name
- Histone H3
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Background
- This core component of the nucleosome can be citrullinated on arginines 2, 8 and 17 by PADI4. These modifications blocks methylation and so represses the transcription
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Gene ID
- 440093
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UniProt
- Q6NXT2
Target
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