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Histone 3 antibody (ciArg2, ciArg8, ciArg17)

The Rabbit Polyclonal anti-Histone 3 antibody has been validated for WB, IHC, ELISA and ICC. It is suitable to detect Histone 3 in samples from Human.
Catalog No. ABIN347087

Quick Overview for Histone 3 antibody (ciArg2, ciArg8, ciArg17) (ABIN347087)

Target

See all Histone 3 (H3) Antibodies
Histone 3 (H3) (Histone H3 (H3))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Histone 3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
  • Binding Specificity

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    ciArg2, ciArg8, ciArg17

    Specificity

    Reacts with human Histone H3 Citrulline at the 3 positions: 2, 8 and 17

    Cross-Reactivity (Details)

    Reacts with mono or di H3-Cit. Not tested in other species. May cross reacts with other species due to sequence homology.

    Purification

    Antiserum

    Immunogen

    Synthetic peptide derived from Nter domain of human Histone H3 containing Citrulline at position 2-8-17

    Isotype

    IgG
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    - IHC : 1/2 000 to 1/20 000 - WB : 1/5 000 to 1/50 000

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Must be reconstituted in distilled water.

    Storage

    4 °C/-20 °C

    Storage Comment

    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

    Expiry Date

    24 months
  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Alternative Name

    Histone H3

    Background

    This core component of the nucleosome can be citrullinated on arginines 2, 8 and 17 by PADI4. These modifications blocks methylation and so represses the transcription

    Gene ID

    440093

    UniProt

    Q6NXT2
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