Cathepsin L Protease (CPL-1) (Mature-Region) antibody

Catalog No. ABIN347097

Product Details

Target: Cathepsin L Protease (CPL-1)

Binding Specificity: Mature-Region

Reactivity: C. elegans

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunoelectron Microscopy (IEM), Western Blotting (WB)

Specificity: Reacts with 36 kDa CPL-1 wild-type protein of C

Cross-Reactivity (Details): elegans. Cross reacts with CPL-1 from ticks (R. microplus).

Purification: Antiserum

Immunogen: Synthetic peptide derived from Mature-region of CPL-1

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
EM (1:50 - 1:200) WB(1:200 - 1:1000)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

References

Popara, Villar, Mateos-Hernández, de Mera, Marina, del Valle, Almazán, Domingos, de la Fuente: "Lesser protein degradation machinery correlates with higher BM86 tick vaccine efficacy in Rhipicephalus annulatus when compared to Rhipicephalus microplus." in: Vaccine, Vol. 31, Issue 42, pp. 4728-35, (2013) (PubMed).

Britton, Murray: "Cathepsin L protease (CPL-1) is essential for yolk processing during embryogenesis in Caenorhabditis elegans." in: Journal of cell science, Vol. 117, Issue Pt 21, pp. 5133-43, (2004) (PubMed).

Target Details

Target: Cathepsin L Protease (CPL-1)

Background: CPL-1 is essential during embryogenesis in C. Elegans

Gene ID: 180111

UniProt: O45734