GAP43 antibody (pSer41)

Catalog No. ABIN350112

This anti-GAP43 antibody is a Sheep Polyclonal antibody detecting GAP43 in IHC. Suitable for Human.

Quick Overview for GAP43 antibody (pSer41) (ABIN350112)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This GAP43 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-GAP43 Antibody

Binding Specificity: pSer41

Purpose: Sheep antibody to phospho S41 GAP 43

Specificity: Specific for GAP-43.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide to phospho S41 of human GAP-43 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat mouse zebra fish and chicken.

Isotype: IgG

Application Details

Application Notes: IHC. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. This antibody may also recognise the unphosphorylated form.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Alternative Name: GAP 43

Background: FUNCTION: This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. SUBUNIT: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence. SUBCELLULAR LOCATION: Cell membrane, Peripheral membrane protein, Cytoplasmic side. Cell projection growth cone membrane, Peripheral membrane protein, Cytoplasmic side. Cell junction synapse. Note: Cytoplasmic surface of growth cone and synaptic plasma membranes.

UniProt: P17677