CACNA2D3
Reactivity: Human
WB, FACS, ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
IHC WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice
Avoid freeze and thaw cycles.
Storage
4 °C,-20 °C
Storage Comment
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A) N-type (CACNA1B) L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G). Subcellular location: Membrane, Single-pass type I membrane protein Miscellaneous: In contrast to CACNA2D1 and CACNA2D2 it does not bind gabapentin an antiepileptic drug.