c-FOS antibody
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- Target See all c-FOS (c-Fos) Antibodies
- c-FOS (c-Fos) (c-Fos)
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Reactivity
- Human
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Host
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Sheep
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Clonality
- Polyclonal
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Conjugate
- This c-FOS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- Sheep antibody to cFos
- Specificity
- Specific for cFos.
- Cross-Reactivity
- Human, Marmoset, Mouse, Rat
- Cross-Reactivity (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogen
- A synthetic peptide from human cFos protein conjugated to blue carrier protein has been used as the antigen.
- Isotype
- IgG
- Top Product
- Discover our top product c-Fos Primary Antibody
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- Application Notes
- IHC WB. Use at a concentration of 10-50 μg,ml. The optimal working concentration should be determined by the end user. Not yet tested in other applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
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- Target
- c-FOS (c-Fos) (c-Fos)
- Alternative Name
- cFos (c-Fos Products)
- Background
- FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction cell proliferation and differentiation. SUBUNIT: Heterodimer. Interacts with DSIPI, this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB SUBCELLULAR LOCATION: Nucleus. INDUCTION: C-fos expression increases upon a variety of stimuli including growth factors cytokines neurotransmitters polypeptide hormones stress and cell injury. SIMILARITY: Belongs to the bZIP family. Fos subfamily SIMILARITY: Contains 1 bZIP domain
- UniProt
- P01100
- Pathways
- S100 Proteins
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