Dynamin 1 antibody

Catalog No. ABIN350299

Product Details anti-Dynamin 1 Antibody

Target: Dynamin 1 (DNM1)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dynamin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit antibody to Dynamin 1

Specificity: Specific for Dynamin 1.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from rat Dynamin conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in human and mouse.

Isotype: IgG

Application Details

Application Notes: IHC WB (confirmed by recombinant protein). A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for Dynamin 1

Target: Dynamin 1 (DNM1)

Alternative Name: Dynamin 1 (DNM1 Products)

Background: Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes in particular endocytosis. Catalytic activity: GTP + H(2)O = GDP + phosphate. Subcellular location: Cytoplasm. Cytoplasm ‰ cytoskeleton.

UniProt: P21575

Pathways: Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling