SORCS3 antibody (C-Term)

Catalog No. ABIN350861

The Rabbit Polyclonal anti-SORCS3 antibody has been validated for WB and IHC. It is suitable to detect SORCS3 in samples from Human.

Quick Overview for SORCS3 antibody (C-Term) (ABIN350861)

Target: SORCS3 (Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORCS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SORCS3 Antibody

Binding Specificity: C-Term

Purpose: Rabbit antibody to SORCS3

Specificity: Specific for SORCS3.

Cross-Reactivity: Human

Cross-Reactivity (Details): Other species not yet tested.

Purification: IgG

Immunogen: A synthetic peptide from the c-terminal region of human SORCS3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 95% identity with mouse sequence.

Isotype: IgG

Application Details

Application Notes: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Expiry Date: 12 months

Target Details for SORCS3

Target: SORCS3 (Sortilin-Related VPS10 Domain Containing Receptor 3 (SORCS3))

Alternative Name: SORCS3

Background: This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins. Subcellular location: Membrane, Single-pass type I membrane protein. Tissue specificity: Highly expressed in brain.

UniProt: Q9UPU3