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PRDM2 antibody (AA 245-573)

This Rabbit Polyclonal antibody specifically detects PRDM2 in WB, IP, IHC (p) and EIA. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN356710

Quick Overview for PRDM2 antibody (AA 245-573) (ABIN356710)

Target

See all PRDM2 Antibodies
PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

Reactivity

Human, Mouse, Rat

Host

  • 54
  • 11
Rabbit

Clonality

  • 55
  • 10
Polyclonal

Conjugate

  • 16
  • 6
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PRDM2 antibody is un-conjugated

Application

  • 35
  • 26
  • 26
  • 25
  • 12
  • 10
  • 7
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Binding Specificity

    • 15
    • 15
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 245-573

    Specificity

    This antibody also recognizes the isoform beta (Riz2) of PRDM2 (185 kDa)

    Purification

    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    Immunogen

    Purified recombinant GST fusion protein encoding aa 245-573 of Rat Riz1. Genename: PRDM2

    Isotype

    Ig Fraction
  • Application Notes

    ELISA: 1/1,000. Western Blot.1/100-1/500. Immunohistochemistry: 1/100-1/500. Immunoprecipitation: 1 μg Pab/100 μg cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    PRDM2 (PR Domain Containing 2, with ZNF Domain (PRDM2))

    Alternative Name

    PRDM2

    Background

    PRDM2 is a 250-kD nuclear protein containing 8 zinc finger motifs. It contains an RB-binding motif that is related to that of the adenovirus E1A oncoprotein, RIZ also shares an antigenic epitope with the C terminus of E1A. It is expressed in human retinoblastoma cells and at low levels in all other human cell lines examined. Using fluorescence in situ hybridization, the PRDM2 gene has been mapped to 1p36. PRDM2 may be a candidate target of 1p36 alterations that commonly occur in neuroendocrine, breast, liver, colon, skin, and lymphoid tumors.Synonyms: GATA-3-binding protein G3B, HUMHOXY1, KMT8, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain zinc finger protein 2, RIZ1, RIZ2, Retinoblastoma protein-interacting zinc finger protein

    Gene ID

    7799, 5874

    UniProt

    Q13029
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