Cadherin 4 antibody (N-Term)

Catalog No. ABIN356865

Product Details anti-Cadherin 4 Antibody

Target: Cadherin 4 (CDH4)

Binding Specificity: AA 182-211, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to CDH4 (N-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide between 182~211 amino acids from the N-terminal region of human CDH4 . Genename: CDH4

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Cadherin 4

Target: Cadherin 4 (CDH4)

Alternative Name: Cadherin-4 (CDH4 Products)

Background: CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.Synonyms: CDH4, Cadherin R, R Cadherin, R-CAD, Retinal Cadherin

Molecular Weight: 100281 Da

Gene ID: 1002, 9606

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size