SULT2B1 antibody (N-Term)

Catalog No. ABIN357809

The Rabbit Polyclonal anti-SULT2B1 antibody has been validated for EIA. It is suitable to detect SULT2B1 in samples from Human.

Quick Overview for SULT2B1 antibody (N-Term) (ABIN357809)

Target: SULT2B1 (Sulfotransferase Family, Cytosolic, 2B, Member 1 (SULT2B1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SULT2B1 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Product Details anti-SULT2B1 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects SULT2B1a/b (N-term).

Purification: Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SULT2B1a/b.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SULT2B1

Target: SULT2B1 (Sulfotransferase Family, Cytosolic, 2B, Member 1 (SULT2B1))

Alternative Name: SULT2B1

Background: Cytosolic sulfotransferases (STs or SULTs) catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. Her et al. (1998) identified an EST with homology to ST enzymes. By PCR with human placental and prostate cDNA as template, they isolated 2 alternatively spliced cDNAs, identical throughout most of their sequences, but having different 5-prime ends. The shorter cDNA, SULT2B1a, encodes a protein of 350 amino acids, the longer cDNA, SULT2B1b, encodes a 365-amino acid protein. Genomic PCR analysis revealed that the gene encoding both cDNAs, SULT2B1, contains 7 exons, with 2 alternative first exons being used to generate SULT2B1a and SULT2B1b. Northern blot analysis revealed that the SULT2B1 gene is expressed as a 1.4-kb transcript predominantly in prostate, placenta, and trachea.Synonyms: Alcohol sulfotransferase, HSST2, Hydroxysteroid sulfotransferase 2, ST2B1, Sulfotransferase 2B1, Sulfotransferase family cytosolic 2B member 1

Molecular Weight: 41307 Da and 39599 Da

Gene ID: 6820

NCBI Accession: NP_004596

UniProt: O00204

Pathways: Steroid Hormone Biosynthesis