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c-FOS antibody (pThr232)

This Rabbit Polyclonal antibody specifically detects c-FOS in EIA. It exhibits reactivity toward Human.
Catalog No. ABIN358282

Quick Overview for c-FOS antibody (pThr232) (ABIN358282)

Target

See all c-FOS (c-Fos) Antibodies
c-FOS (c-Fos) (c-Fos)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This c-FOS antibody is un-conjugated

Application

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Enzyme Immunoassay (EIA)
  • Binding Specificity

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    pThr232

    Specificity

    This antibody detects FOS pThr232.

    Purification

    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr232 of human FOS.

    Isotype

    Ig Fraction
  • Application Notes

    ELISA: 1/1,000. Dot Blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    c-FOS (c-Fos) (c-Fos)

    Alternative Name

    C-Fos

    Background

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.Synonyms: Cellular oncogene fos, FOS, G0/G1 switch regulatory protein 7, G0S7, Proto-oncogene protein c-fos

    Gene ID

    2353, 9606

    UniProt

    P01100

    Pathways

    S100 Proteins
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