c-FOS antibody (pThr232)
Quick Overview for c-FOS antibody (pThr232) (ABIN358282)
Target
See all c-FOS (c-Fos) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr232
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Specificity
- This antibody detects FOS pThr232.
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Purification
- Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
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Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Thr232 of human FOS.
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Isotype
- Ig Fraction
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Application Notes
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ELISA: 1/1,000. Dot Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- c-FOS (c-Fos) (c-Fos)
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Alternative Name
- C-Fos
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Background
- The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.Synonyms: Cellular oncogene fos, FOS, G0/G1 switch regulatory protein 7, G0S7, Proto-oncogene protein c-fos
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Gene ID
- 2353, 9606
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UniProt
- P01100
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Pathways
- S100 Proteins
Target
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