Ectodysplasin A antibody (N-Term)

Catalog No. ABIN358789

This Rabbit Polyclonal antibody specifically detects Ectodysplasin A in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for Ectodysplasin A antibody (N-Term) (ABIN358789)

Target: Ectodysplasin A (EDA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Ectodysplasin A Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to EDA.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EDA.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: Ectodysplasin-A

Background: EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.Synonyms: ED1, ED1-A1, ED1-A2, EDA, EDA1, EDA2, Ectodermal dysplasia protein, HED, STHAGX1, XHED, XLHED

Gene ID: 1896, 9606

UniProt: Q92838

Pathways: Tube Formation