KLK2
Reactivity: Human
WB, IHC (p)
Host: Mouse
Polyclonal
unconjugated
Application Notes
ELISA: 1/1,000. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
Kallikrein 2 (KLK2)
Alternative Name
KLK2 / Kallikrein-2
Background
Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2, encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.Synonyms: Glandular kallikrein-1, Kallikrein 2, Kallikrein2, Tissue kallikrein-2, hGK-1, hK2