Kallikrein 5 antibody (Middle Region)

Catalog No. ABIN358888

This Rabbit Polyclonal antibody specifically detects Kallikrein 5 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Kallikrein 5 antibody (Middle Region) (ABIN358888)

Target: Kallikrein 5 (KLK5)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Kallikrein 5 Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to Kallikrein 5 (KLK5).

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human KLK5.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for Kallikrein 5

Target: Kallikrein 5 (KLK5)

Alternative Name: KLK5 / Kallikrein-5

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.Synonyms: KLK-5, KLK-L2, Kallikrein-Like Protein 2, SCTE, Stratum corneum tryptic enzyme

Gene ID: 25818, 9606

UniProt: Q9Y337

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling