HRG antibody

Catalog No. ABIN360895

This Rat Monoclonal antibody specifically detects HRG in WB. It exhibits reactivity toward Mouse.

Quick Overview for HRG antibody (ABIN360895)

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This HRG antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 9G42

Product Details anti-HRG Antibody

Specificity: This antibody detects Mouse HPRG in Western blotting.

Purification: Affinity Chromatography on Protein A/G. 0.2 µm Filteration.

Immunogen: Purified Mouse Recombinant HPRG protein

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL

Buffer: PBS, None

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HRG

Target: HRG (Histidine-Rich Glycoprotein (HRG))

Alternative Name: Histidine-Rich Glycoprotein / HRG

Background: HRG (histidine-rich glycoprotein) contains two cystatin-like domains and is located in plasma and platelets. The physiological function is not yet known. It binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin, and the lysine-binding site of plasminogen. A potential prothrombotic effect of HRG is indicated by the inhibition of fibrinolysis and the reduction of inhibition of coagulation. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.Synonyms: HPRG, Histidine-proline-rich glycoprotein

Gene ID: 3273

NCBI Accession: NP_000403

UniProt: P04196