F11R antibody (Extracellular Domain)

Catalog No. ABIN360921

The Rat Monoclonal anti-F11R antibody (Clone 1M21) (ABIN360921) specifically detects F11R in WB. The antibody is reactive with Mouse samples.

Quick Overview for F11R antibody (Extracellular Domain) (ABIN360921)

Target: F11R (F11 Receptor (F11R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1M21

Product Details anti-F11R Antibody

Binding Specificity: Extracellular Domain

Purification: Purified

Immunogen: Recombinant protein of JAM-A extracellular domain

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: Protein A/G affinity chromatography

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: CD321 / JAM1

Background: Junctional Adhesion Molecule 1 (JAM1) seems to play a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1

Gene ID: 10090

UniProt: O88792

Pathways: Cell-Cell Junction Organization