ICAM1 antibody (pTyr512)
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- Target See all ICAM1 Antibodies
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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Binding Specificity
- pTyr512
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ICAM1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- The antibody detects endogenous level of ICAM-1 only when phosphorylated at tyrosine 512.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Immunogen
- Peptide sequence around phosphorylation site of pTyr512 (K-K-Y (p) -R-L) derived from Human ICAM-1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Isotype
- IgG
- Top Product
- Discover our top product ICAM1 Primary Antibody
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anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 201-300) antibody
ICAM1 Reactivity: Human, Mouse, Rat, Rabbit WB, FACS, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 198-537) antibodyICAM1 Reactivity: Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) antibodyICAM1 Reactivity: Human, Rat, Cow WB, FACS, ELISA, IHC (p), ICC Host: Mouse Monoclonal MEM-111 unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 102-306) antibodyICAM1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibodyICAM1 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C2 unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (pTyr512) antibodyICAM1 Reactivity: Human, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibodyICAM1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 27-209) antibodyICAM1 Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 313-327) antibodyVerified ICAM1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-163) antibodyICAM1 Reactivity: Human WB, FACS, ELISA Host: Mouse Monoclonal 3A5G12 unconjugated
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- Application Notes
- Western blotting: 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Target
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- Alternative Name
- ICAM-1 (ICAM1 Products)
- Target Type
- Viral Protein
- Background
- ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
- Molecular Weight
- 92 kDa
- NCBI Accession
- NP_000192
- UniProt
- P05362
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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