P4HB antibody (full length)

Catalog No. ABIN363358

This Rabbit Polyclonal antibody specifically detects P4HB in WB, IP, IF, ICC, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat, Cow and Monkey.

Quick Overview for P4HB antibody (full length) (ABIN363358)

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivity: Human, Mouse, Rat, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HB antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-P4HB Antibody

Binding Specificity: full length

Specificity: Reacts with PDIA2 from human, mouse, rat, bovine and primate

Purification: Antiserum

Immunogen: Purified full-length PDI liver protein

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/5 000 to 1/20 000 - IHC - F : 1/100 to 1/1 000 - IHC - P : 1/100 to 1/500 - IP: 1-3 μg - WB: 1:10000-1:20000

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for P4HB

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Alternative Name: Protein disulfide isomerase

Background: Protein disulfide isomerase (PDI) is an acidic 55 kDa thyroid hormone-binding protein that appears to be identical to the glial-p55 protein.It has been suggested to be involved in disulfide-bond formation and isomerization, as well as the reduction of disulfide bonds in proteins.It may also play a role in the thyroid hormone-dependent regulation of actin polymerization and the degradation of the membrane-associated protein type II iodothyronine 5'-deiodinase (5'D-II).

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism