PLIN5 antibody (AA 300-400)

Catalog No. ABIN363617

The Rabbit Polyclonal anti-PLIN5 antibody has been validated for WB and IHC. It is suitable to detect PLIN5 in samples from Human, Mouse and Cow.

Quick Overview for PLIN5 antibody (AA 300-400) (ABIN363617)

Target: PLIN5 (Perilipin 5 (PLIN5))

Reactivity: Human, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLIN5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PLIN5 Antibody

Binding Specificity: AA 300-400

Specificity: Reacts with OXPAT from human, mouse and bovine

Cross-Reactivity (Details): Porcine (94 % ), Sheep (94 %).

Purification: Antigen affinity purified

Immunogen: Synthetic peptide made to a region of the human OXPAT protein within residues 300-400

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC(1.0 - 5.0 μg/mL) WB(0.5 - 2.0 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.01 mg/mL

Buffer: PBS, glycerol 30 % , Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for PLIN5

Target: PLIN5 (Perilipin 5 (PLIN5))

Alternative Name: OXPAT

Background: OXPAT is a novel PAT-1 protein that is expressed in highly oxidative tissues.Lipid droplet proteins of the PAT family regulate cellular neutral lipid stores.OXPAT is induced by physiological (fasting), pathophysiological (insulin deficiency), pharmacological (peroxisome proliferator-activated receptor [PPAR] agonists), and genetic (muscle-specific PPAR alpha overexpression) disturbances that increase fatty acid utilization.It is suggested that OXPAT is a marker for PPAR activation and fatty acid oxidation.As well, it may contribute to adaptive responses to the fatty acid responsibility that accompanies fasting, insulin deficiency, and overnutrition, responses that are defective in obesity and type 2 diabetes.