CD81 antibody (Biotin)

Catalog No. ABIN371122

This Hamster Monoclonal antibody specifically detects CD81 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for CD81 antibody (Biotin) (ABIN371122)

Target: CD81

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD81 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: 2F7

Product Details anti-CD81 Antibody (Biotin)

Characteristics: Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

Immunogen: Mouse epithelial cell line PAM212.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry: Identification and enumeration of CD81+ cells (< / = 1 μg/10^6 cells). (Ref.2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD81

Target: CD81

Alternative Name: CD81 / TAPA1

Background: TAPA1, or CD81, is a member of the transmembrane 4 superfamily, also known as the Tetraspanin family. Most of these members are cell surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TAPA1 is a cell surface glycoprotein that is known to complex with integrins. It appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. TAPA1 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

UniProt: P35762

Pathways: Inositol Metabolic Process, Hepatitis C