CD81 antibody

Catalog No. ABIN371124

This anti-CD81 antibody is a Hamster Monoclonal antibody detecting CD81 in FACS, IP, Func and IHC (fro). Suitable for Mouse.

Quick Overview for CD81 antibody (ABIN371124)

Target: CD81

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD81 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 2F7

Product Details anti-CD81 Antibody

Characteristics: Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

Endotoxin Level: Low Endotoxin

Immunogen: Mouse epithelial cell line PAM212.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry: Identification and enumeration of CD81+ cells. Immunoprecipitation. Immunohistochemistry on Frozen Sections. In vitro blocking of thymocyte interactions with CD81. See Ref.2 for more details.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS without preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD81

Target: CD81

Alternative Name: CD81 / TAPA1

Background: TAPA1, or CD81, is a member of the transmembrane 4 superfamily, also known as the Tetraspanin family. Most of these members are cell surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TAPA1 is a cell surface glycoprotein that is known to complex with integrins. It appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. TAPA1 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

UniProt: P35762

Pathways: Inositol Metabolic Process, Hepatitis C