T Cell Receptor (TCR) V beta 1 antibody

Catalog No. ABIN371346

This anti- antibody is a Mouse Monoclonal antibody detecting in FACS, Func, IHC (fro) and IP. Suitable for Chicken.

Quick Overview for T Cell Receptor (TCR) V beta 1 antibody (ABIN371346)

Target: T Cell Receptor (TCR) V beta 1

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Clone: TCR2

Product Details

Characteristics: Synonyms: TCR-Vbeta1, Vbeta-1, VB1, TCRA, TCRB, TCR-VB1, T Cell Receptor alpha/beta

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections). (Ref.7)Immunoprecipitation. In ovo suppression of the development of TCR-Vbeta 1. (Ref.5,6)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details

Target: T Cell Receptor (TCR) V beta 1

Alternative Name: T Cell Receptor (TCR) V beta-1

Background: The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.Synonyms: T Cell Receptor alpha/beta, TCR-VB1, TCR-Vbeta1, TCRA, TCRB, VB1, Vbeta-1