BU-1A / B6.1 antibody (PE)

Catalog No. ABIN371432

The Mouse Monoclonal anti-BU-1A / B6.1 antibody has been validated for FACS. It is suitable to detect BU-1A / B6.1 in samples from Chicken.

Quick Overview for BU-1A / B6.1 antibody (PE) (ABIN371432)

Target: BU-1A / B6.1

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This BU-1A / B6.1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: AV20

Product Details anti-BU-1A / B6.1 Antibody (PE)

Characteristics: Synonyms: B-Cell Marker

Immunogen: Bursal cells from one-day-old H. B15 (Bu-1a/b) strain chickens. (Ref. 1)

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for BU-1A / B6.1

Target: BU-1A / B6.1

Background: The Bu1 [chB6] molecule is expressed on chicken B cells throughout most of their development, as well as on some non lymphoid cells. It has long been used as an allotypic marker in important studies of B cell development, though its function is unknown. It has no recognizable similarity to known mammalian molecules and thus represents a unique B cell marker. Its presence in chickens may be related to differences in the properties of B cell development between chickens and mammalian species. The sequences of the different alleles of this gene revealed a higher level of polymorphism than expected. A restriction fragment length polymorphism linked to the CHB6 gene has been used to determine its location on the linkage map of the chicken genome, which will allow the definitive evaluation of reported associations with disease resistance.Synonyms: B-Cell Marker